Human Papillomavirus (HPV) Nucleic Acid Detection Kit (PCR - Fluorescent Probe Method) CapitalBio

Detection Targets

• Detection of HPV 16/18/26/31/33/35/39/45/51/52/53/56/58/59/66/68/73/82; 

• HPV 16/18 genotyping

Features

• High sensitivity: The LOD is 500 copies/ml;

• Quick workflow: It only takes 1.5 h to complete the whole workflow;

• Multiplex: One tube for detecting 18 HPV types and HPV 16/18 genotyping;

• Convenient test: Pre-aliquoted lyphilized nanoparticles enable reactions as soon as samples have been added, saving labor and effort.

Test Method

The kit is designed based on PCR - fluorescent probe technology

Sample Types

Female cervical exfoliated epithelial cells

Clinical Significance

Initial screening of cervical lesions and cervical cancer in large-scale population ;

Triage management for patients with atypical squamous cells of undetermined significance (ASCUS);

Monitoring and follow-up after treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer.

Order Information

Background Information

Human papillomaviruses (HPVs) are a large and diverse group of epitheliotropic double-stranded DNA viruses. There are up to 225 types of HPVs, and about 15 of them are high-risk HPVs, which can lead to invasive carcinomas. It was reported that infection with at least 1 high-risk HPV will occur during the lifetime of 60% of sexually active individuals. They are often eliminated by the immune system within 1 or 2 years after exposure. The viruses in the remaining cases that persists for a long time lead to lesions that can bring malignancies. Therefore, early diagnosis of HPV infection and HPV induced lesions is highly important to prevent cancer development.